Which of the following molecules plays a crucial role in the regulation of hematopoietic stem cell mobilization from the bone marrow to the peripheral blood?

A Stromal cell-derived factor 1 (SDF-1)
B Granulocyte-colony stimulating factor (G-CSF) ✓
C Interleukin-8 (IL-8)
D Vascular endothelial growth factor (VEGF)

Explanation

Granulocyte-colony stimulating factor (G-CSF) is a key regulator of hematopoietic stem cell mobilization from the bone marrow to the peripheral blood, particularly in response to injury or infection.

Source

Blood journal
Hematology Hematology: Hematopoiesis Hematology: Hematopoiesis Hard MEDICAL Confidence: medium