Which of the following factors influences the fate decision of common myeloid progenitors towards either granulocyte or monocyte lineage?

A PU.1
B GATA-1
C C/EBPα
D All of the above ✓

Explanation

The fate decision of common myeloid progenitors towards either granulocyte or monocyte lineage is influenced by a combination of transcription factors including PU.1, GATA-1, and C/EBPα, which regulate the expression of lineage-specific genes.

Source

Nature Reviews Immunology
Hematology Hematology: Hematopoiesis Hematology: Hematopoiesis Hard MEDICAL Confidence: medium