Which of the following coagulation disorders is characterized by an deficiency of plasminogen activator inhibitor-1 (PAI-1)?
A
Bleeding disorder due to decreased fibrinolysis
B
Thrombotic disorder due to increased fibrinolysis
C
Thrombotic disorder due to decreased fibrinolysis
D
Bleeding disorder due to increased fibrinolysis
✓
Explanation
A deficiency of PAI-1 leads to an increase in fibrinolysis, resulting in a bleeding disorder.
Source
Williams Hematology
Hematology
Hematology: Coagulation Disorders
Hematology: Coagulation Disorders
Hard
MEDICAL
Confidence: medium
