Which of the following statements is true regarding the condition known as thrombotic thrombocytopenic purpura (TTP)?

A It is characterized by a deficiency of von Willebrand factor-cleaving protease (ADAMTS13) ✓
B It is caused by an autoimmune response to platelet antigens
C It is typically associated with a low risk of recurrent thrombosis
D It is primarily treated with aspirin and clopidogrel

Explanation

Thrombotic thrombocytopenic purpura (TTP) is a rare blood disorder characterized by a deficiency of von Willebrand factor-cleaving protease (ADAMTS13), leading to the formation of blood clots in small blood vessels throughout the body.

Source

New England Journal of Medicine
Hematology Hematology: Coagulation Disorders Hematology: Coagulation Disorders Hard MEDICAL Confidence: high