What is the primary function of the chemokine CXCL12 in hematopoiesis?

A To stimulate the proliferation of hematopoietic stem cells
B To regulate the migration and homing of hematopoietic stem cells to the bone marrow ✓
C To inhibit the differentiation of hematopoietic stem cells
D To induce the apoptosis of hematopoietic stem cells

Explanation

CXCL12 is a chemokine that plays a crucial role in the migration and homing of hematopoietic stem cells to the bone marrow, where they can interact with the hematopoietic niche and undergo differentiation and proliferation.

Source

Blood journal
Hematology Hematology: Hematopoiesis Hematology: Hematopoiesis Medium MEDICAL Confidence: high