Which of the following enzymes is involved in the regulation of heme synthesis in hematopoietic cells?

A Aminolevulinic acid synthase (ALAS) ✓

B Ferrochelatase

C Uroporphyrinogen decarboxylase

D Porphobilinogen deaminase

Explanation

Aminolevulinic acid synthase (ALAS) is the first and rate-limiting enzyme in the heme synthesis pathway, and its regulation is critical for the production of heme in hematopoietic cells.

Source

Nature journal

Hematology Hematology: Hematopoiesis Hematology: Hematopoiesis Hard MEDICAL Confidence: high

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Which of the following enzymes is involved in the regulation of heme synthesis in hematopoietic cells?

Explanation

Source

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