A patient with anemia is found to have a high level of soluble transferrin receptor (sTfR) in their blood. What does this indicate?

A Iron deficiency anemia
B Anemia of chronic disease
C Erythropoietic activity and possible iron deficiency ✓
D Vitamin B12 deficiency

Explanation

Soluble transferrin receptor (sTfR) is a marker of erythropoietic activity and can be elevated in cases of iron deficiency or increased red blood cell production, making it a useful indicator in distinguishing between different types of anemia.

Source

Blood Journal
Hematology Hematology: Anemia Hematology: Anemia Medium MEDICAL Confidence: high