A patient with a history of transfusion reactions has developed antibodies against the P1 antigen. What is the most likely consequence of this antibody formation?

A Immediate hemolysis of transfused red blood cells
B Delayed hemolysis of transfused red blood cells ✓
C Enhanced phagocytosis of transfused red blood cells
D No significant clinical consequence

Explanation

The formation of antibodies against the P1 antigen can lead to a delayed hemolytic transfusion reaction, as the P1 antigen is not as immunogenic as other blood group antigens, but can still cause a significant reaction.

Source

Transfusion Medicine Textbook
Hematology Hematology: Blood Grouping and Crossmatching Hematology: Blood Grouping and Crossmatching Medium MEDICAL Confidence: medium