What is the significance of the Kell blood group system in hemolytic disease of the newborn?

A It is the most common cause of HDN
B It is a rare cause of HDN, but can be severe ✓
C It is not associated with HDN
D It is only relevant in adult transfusion reactions

Explanation

The Kell blood group system is a significant cause of hemolytic disease of the newborn (HDN), although it is less common than the Rh and ABO systems. Anti-Kell antibodies can cause severe HDN.

Mnemonic

Kell = Key to unlocking HDN causes

Source

Medical textbooks and journals
Hematology Hematology: Blood Grouping and Crossmatching Hematology: Blood Grouping and Crossmatching Medium MEDICAL Confidence: high