Which of the following cellular processes is crucial for the maintenance of hematopoietic stem cell quiescence?

A Cell cycle progression
B Apoptosis
C Autophagy
D Epigenetic regulation
Epigenetic regulation, including DNA methylation and histone modification, plays a crucial role in maintaining hematopoietic stem cell quiescence by regulating gene expression.
Orkin et al. (2015) Nature Immunology
Hematology Hematology: Hematopoiesis Hematology: Hematopoiesis Hard MEDICAL Confidence: medium