Which of the following cell types is responsible for the production of osteopontin, a protein that regulates hematopoietic stem cell homing and retention in the bone marrow?

A Osteoblasts
B Osteoclasts
C Adipocytes
D Mesenchymal stromal cells ✓

Explanation

Mesenchymal stromal cells, also known as marrow stromal cells, produce osteopontin, which plays a crucial role in regulating hematopoietic stem cell homing and retention in the bone marrow.

Source

Blood journal
Hematology Hematology: Hematopoiesis Hematology: Hematopoiesis Hard MEDICAL Confidence: medium