Which vitamin acts as a coenzyme for the enzyme pyruvate dehydrogenase, playing a critical role in the conversion of pyruvate to acetyl-CoA?

A Vitamin B1 (Thiamine) ✓
B Vitamin B2 (Riboflavin)
C Vitamin B3 (Niacin)
D Vitamin B5 (Pantothenic acid)

Explanation

Thiamine diphosphate, a derivative of Vitamin B1, serves as a coenzyme for pyruvate dehydrogenase, facilitating the conversion of pyruvate to acetyl-CoA.

Source

Harper's Biochemistry
Vitamins Biochemistry Water-Soluble Vitamins Medium MEDICAL Confidence: high