Which of the following types of anemia is characterized by a defect in the synthesis of heme?

A Iron-deficiency anemia
B Vitamin B12 deficiency anemia
C Porphyrin deficiency anemia
D Sideroblastic anemia ✓

Explanation

Sideroblastic anemia is a type of anemia characterized by a defect in the synthesis of heme, leading to the accumulation of iron in the mitochondria of red blood cell precursors.

Mnemonic

Sidero = Side + Blast = immature cells with iron

Source

Harrison's Principles of Internal Medicine
Hematology Hematology: Anemia Hematology: Anemia Medium MEDICAL Confidence: high