Which of the following factors is responsible for the regulation of hematopoietic stem cell mobilization from the bone marrow to the peripheral blood?

A Stromal cell-derived factor-1 (SDF-1)
B Granulocyte-colony stimulating factor (G-CSF) ✓
C Erythropoietin (EPO)
D Thrombopoietin (TPO)

Explanation

Granulocyte-colony stimulating factor (G-CSF) is a key regulator of hematopoietic stem cell mobilization from the bone marrow to the peripheral blood. It induces the release of stem cells from their niche and promotes their migration to the bloodstream.

Source

Blood Journal
Hematology Hematology: Hematopoiesis Hematology: Hematopoiesis Medium MEDICAL Confidence: medium