Which of the following enzymes plays a crucial role in the regulation of heme synthesis in hematopoietic cells?

A Aminolevulinic acid synthase
B Ferrochelatase
C Uroporphyrinogen decarboxylase
D Porphobilinogen deaminase
Aminolevulinic acid synthase is the first and rate-limiting enzyme in the heme biosynthesis pathway, and its regulation is critical for the production of heme in hematopoietic cells.
Blood Journal
Hematology Hematology: Hematopoiesis Hematology: Hematopoiesis Medium MEDICAL Confidence: high