Which of the following factors influences the fate decision of hematopoietic stem cells towards the myeloid or lymphoid lineage?

A Notch signaling
B Wnt/β-catenin signaling
C Transforming growth factor-β (TGF-β) signaling
D All of the above ✓

Explanation

Notch, Wnt/β-catenin, and TGF-β signaling pathways all play important roles in regulating the fate decision of hematopoietic stem cells towards the myeloid or lymphoid lineage.

Source

Blood
Hematology Hematology: Hematopoiesis Hematology: Hematopoiesis Medium MEDICAL Confidence: high