Which of the following enzymes plays a crucial role in the development of Alzheimer's disease by cleaving the amyloid precursor protein to form beta-amyloid peptides?

A Acetylcholinesterase
B Butyrylcholinesterase
C Beta-secretase ✓
D Alpha-chymotrypsin

Explanation

Beta-secretase is an enzyme that cleaves the amyloid precursor protein to form beta-amyloid peptides, which accumulate in the brains of individuals with Alzheimer's disease.

Mnemonic

'Beta' Breaks Amyloid, Secretly Ensuring Alzheimer's Troubles

Source

Research articles on Alzheimer's disease
Enzymes in Disease Biochemistry Neurodegenerative Diseases Hard MEDICAL Confidence: high