Which enzyme's deficiency is associated with the development of Gaucher's disease, a genetic disorder characterized by the accumulation of glucocerebroside in cells?

A Glucocerebrosidase ✓
B Hexosaminidase A
C Alpha-galactosidase A
D Beta-galactosidase

Explanation

Gaucher's disease is caused by a deficiency of the enzyme glucocerebrosidase, which is responsible for breaking down glucocerebroside into glucose and ceramide.

Mnemonic

Gaucher = Glucocerebroside Accumulation, Understand Cher Helps Enzyme Recognition

Source

NCERT Class 12 Biochemistry
Enzymes in Disease Biochemistry Lysosomal Storage Diseases Medium MEDICAL Confidence: high