Which of the following anemias is characterized by a lack of intrinsic factor, leading to impaired vitamin B12 absorption?

A Pernicious anemia ✓
B Iron deficiency anemia
C Vitamin deficiency anemia
D Anisocytosis

Explanation

Pernicious anemia is characterized by a lack of intrinsic factor, leading to impaired vitamin B12 absorption, resulting in megaloblastic anemia.

Mnemonic

_Per_nicious = _per_manent lack

Source

Harrison's Principles of Internal Medicine
Hematology Hematology: Anemia Hematology: Anemia Easy MEDICAL Confidence: high