Which enzyme is involved in the metabolism of homocysteine, and its deficiency is associated with an increased risk of cardiovascular disease and neural tube defects?

A Methionine synthase
B Cystathionine beta-synthase ✓
C Homocysteine methyltransferase
D Betaine homocysteine methyltransferase

Explanation

The enzyme cystathionine beta-synthase is involved in the metabolism of homocysteine. Its deficiency is associated with an increased risk of cardiovascular disease and neural tube defects.

Source

Biochemistry journals
Enzymes in Disease Biochemistry Amino Acid Metabolism Disorders Hard MEDICAL Confidence: high