What is the primary enzyme responsible for the breakdown of glycogen to glucose in the liver, and its deficiency leads to a rare genetic disorder?

A Glucosidase
B Debranching enzyme
C Phosphorylase ✓
D Amylase

Explanation

The primary enzyme responsible for the breakdown of glycogen to glucose in the liver is phosphorylase. Its deficiency leads to a rare genetic disorder known as Hers' disease.

Source

Biochemistry textbooks
Enzymes in Disease Biochemistry Glycogen Metabolism Disorders Medium MEDICAL Confidence: high