What is the term for the process by which red blood cells are removed from the circulation by the spleen, leading to anemia in certain conditions?

A Hemolysis
B Hemosiderosis
C Extramedullary hematopoiesis
D Splenic sequestration ✓

Explanation

Splenic sequestration refers to the process by which the spleen removes red blood cells from the circulation, leading to anemia in conditions such as hereditary spherocytosis or sickle cell disease.

Mnemonic

Spleen = Sieve → filters out RBCs

Source

Robbins and Cotran Pathologic Basis of Disease
Hematology Hematology: Anemia Hematology: Anemia Medium MEDICAL Confidence: high