What is the role of the enzyme acid alpha-glucosidase in the progression of Pompe disease?

A Breakdown of glycogen to glucose ✓
B Synthesis of glycogen from glucose
C Degradation of glycogen to glucose-1-phosphate
D Phosphorylation of glycogen

Explanation

Pompe disease is caused by a deficiency in acid alpha-glucosidase, leading to accumulation of glycogen in lysosomes. The enzyme breaks down glycogen to glucose.

Source

NCBI Genetics Home Reference
Enzymes in Disease Biochemistry Lysosomal Storage Diseases Hard MEDICAL Confidence: high