What is the role of hemoglobin's alpha-globin subunit in the formation of hemoglobin tetramers?

A It initiates the assembly of the hemoglobin molecule
B It binds to heme groups to form a stable complex
C It interacts with beta-globin subunits to form the tetrameric structure ✓
D It regulates the oxygen-binding affinity of hemoglobin

Explanation

The alpha-globin subunit interacts with beta-globin subunits to form the tetrameric structure of hemoglobin, which is essential for its function in oxygen transport.

Source

Guyton and Hall Textbook of Medical Physiology
Hematology Hematology: Hemoglobin and Oxygen Transport Hematology: Hemoglobin and Oxygen Transport Medium MEDICAL Confidence: high