What is the role of enzyme acid alpha-glucosidase in the human body, and how is its deficiency related to a specific disease?

A Breakdown of glycogen, and its deficiency leads to Pompe disease ✓
B Synthesis of glucose, and its deficiency leads to diabetes
C Degradation of proteins, and its deficiency leads to muscular dystrophy
D Production of ATP, and its deficiency leads to mitochondrial myopathies

Explanation

Acid alpha-glucosidase is an enzyme responsible for breaking down glycogen in lysosomes. Its deficiency leads to the accumulation of glycogen in cells, causing Pompe disease, a type of glycogen storage disorder.

Source

Medical Biochemistry textbook by Mark A. Levy
Enzymes in Disease Biochemistry Lysosomal Storage Diseases Hard MEDICAL Confidence: high