What is the role of CD46 in the regulation of complement activation on red blood cells?

A It acts as a receptor for complement component C3b
B It inhibits the activation of the alternative complement pathway ✓
C It regulates the expression of blood group antigens
D It enhances the phagocytosis of red blood cells

Explanation

CD46 is a complement regulatory protein that inhibits the activation of the alternative complement pathway on red blood cells, preventing unnecessary destruction.

Source

Journal of Immunology
Hematology Hematology: Blood Grouping and Crossmatching Hematology: Blood Grouping and Crossmatching Hard MEDICAL Confidence: high