What is the relationship between the enzyme superoxide dismutase and the disease amyotrophic lateral sclerosis?

A Superoxide dismutase deficiency leads to increased risk of ALS ✓
B Superoxide dismutase overexpression causes ALS
C Superoxide dismutase has no role in ALS
D Superoxide dismutase mutation is a rare cause of ALS

Explanation

Mutations in the superoxide dismutase gene have been linked to an increased risk of developing amyotrophic lateral sclerosis (ALS), a progressive neurodegenerative disease.

Source

Scientific research articles
Enzymes in Disease Biochemistry Neurodegenerative Diseases Hard MEDICAL Confidence: high