How does the enzyme glucocerebrosidase relate to the disease Gaucher's disease?
A
Glucocerebrosidase deficiency leads to accumulation of glucose in cells
B
Glucocerebrosidase overexpression causes Gaucher's disease
C
Glucocerebrosidase is not involved in Gaucher's disease
D
Glucocerebrosidase deficiency leads to accumulation of glucocerebroside in cells
✓
Explanation
Gaucher's disease is caused by a deficiency of the enzyme glucocerebrosidase, leading to the accumulation of glucocerebroside in cells, particularly in macrophages.
Enzymes in Disease
Biochemistry
Lysosomal Storage Diseases
Medium
MEDICAL
Confidence: high