What is the primary site of hematopoiesis in a fetus during the second trimester?

A Yolk sac
B Liver ✓
C Spleen
D Bone marrow

Explanation

During the second trimester, the liver is the primary site of hematopoiesis in a fetus, producing blood cells until the bone marrow takes over later in development.

Source

Guyton and Hall Textbook of Medical Physiology
Hematology Hematology: Hematopoiesis Hematology: Hematopoiesis Easy MEDICAL Confidence: high