What is the clinical significance of detecting anti-M antibodies in a patient's serum?

A It can cause hemolytic disease of the newborn
B It can lead to a delayed hemolytic transfusion reaction
C It can cause an acute hemolytic transfusion reaction
D It is a neutral antibody with no clinical significance
Anti-M antibodies can cause a delayed hemolytic transfusion reaction, which can be severe and even life-threatening.
Medical Literature
Hematology Hematology: Blood Grouping and Crossmatching Hematology: Blood Grouping and Crossmatching Medium MEDICAL Confidence: high