What is the purpose of using 0.8% saline solution in the preparation of red blood cells for transfusion?

A To enhance the expression of ABO antigens
B To reduce the viscosity of the red blood cell suspension
C To maintain the osmotic balance and prevent hemolysis ✓
D To activate the complement system and remove antibodies

Explanation

The use of 0.8% saline solution in the preparation of red blood cells for transfusion helps to maintain the osmotic balance and prevent hemolysis, ensuring the viability and integrity of the red blood cells during storage and transportation.

Source

AABB Technical Manual
Hematology Hematology: Blood Grouping and Crossmatching Hematology: Blood Grouping and Crossmatching Medium MEDICAL Confidence: high