What is the significance of the Rh blood group system in hemolytic disease of the newborn?

A It causes anemia in the newborn
B It leads to jaundice in the newborn
C It can cause the breakdown of red blood cells in the newborn ✓
D It has no role in hemolytic disease of the newborn

Explanation

The Rh blood group system can cause an immune reaction when an Rh-negative mother carries an Rh-positive fetus, leading to the breakdown of red blood cells in the newborn.

Source

Robbins and Cotran Pathologic Basis of Disease
Hematology Hematology: Blood Grouping and Crossmatching Hematology: Blood Grouping and Crossmatching Medium MEDICAL Confidence: high