Which of the following blood group antigens is associated with a higher risk of hemolytic disease of the newborn?

A RhD antigen ✓
B Kell antigen
C Duffy antigen
D MNS antigen

Explanation

The RhD antigen is a major contributor to hemolytic disease of the newborn, particularly if an RhD-negative mother is sensitized to RhD-positive blood.

Source

Williams Hematology
Hematology Hematology: Blood Grouping and Crossmatching Hematology: Blood Grouping and Crossmatching Hard MEDICAL Confidence: high