What is the primary purpose of using a 'major crossmatch' in blood transfusion?

A To detect antibodies against the recipient's red blood cells
B To detect antibodies against the donor's red blood cells ✓
C To determine the ABO blood group of the donor and recipient
D To determine the Rh blood type of the donor and recipient

Explanation

A major crossmatch is used to detect antibodies against the donor's red blood cells in the recipient's serum, which helps to prevent a hemolytic transfusion reaction.

Source

Medical Laboratory Technology textbook
Hematology Hematology: Blood Grouping and Crossmatching Hematology: Blood Grouping and Crossmatching Easy MEDICAL Confidence: high