What is the primary function of the von Willebrand factor-cleaving protease, ADAMTS13, in the coagulation cascade?

A To activate factor VIII
B To cleave von Willebrand factor ✓
C To inhibit platelet aggregation
D To enhance fibrinolysis

Explanation

ADAMTS13 is a metalloprotease that cleaves von Willebrand factor, regulating its activity and preventing excessive platelet aggregation.

Source

Blood journal, 2019
Hematology Hematology: Coagulation Disorders Hematology: Coagulation Disorders Hard MEDICAL Confidence: high