Which of the following coagulation disorders is characterized by a deficiency of the enzyme ADAMTS13, leading to the formation of ultra-large von Willebrand factor multimers?

Thrombotic thrombocytopenic purpura is a rare blood disorder characterized by a deficiency of the enzyme ADAMTS13, which leads to the formation of ultra-large von Willebrand factor multimers and subsequent platelet activation and thrombosis.