What is the mechanism by which protein C exerts its anticoagulant effect?

A By inhibiting the activity of factor Xa
B By enhancing the activity of antithrombin III
C By inactivating factors Va and VIIIa ✓
D By stimulating the production of tissue factor pathway inhibitor

Explanation

Protein C is a vitamin K-dependent serine protease that exerts its anticoagulant effect by inactivating factors Va and VIIIa, which are essential for the coagulation cascade.

Source

Hematology: Clinical Principles and Applications
Hematology Hematology: Coagulation Disorders Hematology: Coagulation Disorders Hard MEDICAL Confidence: high