A patient with anemia due to chronic inflammation has which of the following cytokines elevated, contributing to the pathogenesis of anemia of chronic disease?
Explanation
Tumor Necrosis Factor-alpha (TNF-alpha) is a pro-inflammatory cytokine that plays a significant role in the pathogenesis of anemia of chronic disease. It contributes to the suppression of erythropoiesis and alterations in iron metabolism, characteristic of this condition.
Source
Blood Journal