What is the primary function of the hemoglobin-haptoglobin-scavenger receptor CD163 in the context of anemia?

A To remove free hemoglobin from the circulation ✓
B To transport iron from the liver to the bone marrow
C To stimulate erythropoiesis in response to hypoxia
D To inhibit the production of hepcidin

Explanation

The hemoglobin-haptoglobin-scavenger receptor CD163 plays a crucial role in removing free hemoglobin from the circulation, thereby preventing oxidative damage and inflammation.

Source

Blood journal
Hematology Hematology: Anemia Hematology: Anemia Hard MEDICAL Confidence: high