Which of the following anemias is characterized by an autosomal dominant inheritance pattern and is caused by a mutation in the ALAS2 gene?

A Sideroblastic anemia ✓
B Pyruvate kinase deficiency
C Glucose-6-phosphate dehydrogenase deficiency
D Hereditary spherocytosis

Explanation

X-linked sideroblastic anemia is caused by a mutation in the ALAS2 gene and has an autosomal dominant inheritance pattern.

Source

Orphanet Journal of Rare Diseases
Hematology Hematology: Anemia Hematology: Anemia Hard MEDICAL Confidence: high