Which of the following is a key regulator of hematopoietic stem cell self-renewal and differentiation?

A Wnt/β-catenin pathway
B Notch signaling pathway
C Hedgehog signaling pathway
D TGF-β signaling pathway
The Wnt/β-catenin pathway plays a crucial role in regulating hematopoietic stem cell self-renewal and differentiation.
Nature Reviews Immunology
Hematology Hematology: Hematopoiesis Hematology: Hematopoiesis Medium MEDICAL Confidence: high