What is the function of the aryl hydrocarbon receptor (AhR) in the regulation of hematopoietic stem cell development and function?

A It regulates the expression of genes involved in HSC self-renewal ✓
B It modulates the activity of transcription factors involved in HSC differentiation
C It has no effect on HSC development and function
D It regulates the metabolism of HSCs

Explanation

The aryl hydrocarbon receptor (AhR) plays a role in regulating the expression of genes involved in hematopoietic stem cell self-renewal and development.

Source

Scientific literature
Hematology Hematology: Hematopoiesis Hematology: Hematopoiesis Hard MEDICAL Confidence: high