What is the role of osteoblasts in the hematopoietic niche?

A They produce cytokines that inhibit hematopoiesis
B They produce osteopontin, which supports hematopoietic stem cell maintenance ✓
C They are involved in the degradation of hematopoietic growth factors
D They are not involved in the regulation of hematopoiesis

Explanation

Osteoblasts produce osteopontin, which is a protein that supports the maintenance of hematopoietic stem cells in the bone marrow niche.

Source

Blood journal
Hematology Hematology: Hematopoiesis Hematology: Hematopoiesis Medium MEDICAL Confidence: high