Which of the following cytokines plays a crucial role in the regulation of hematopoietic stem cell mobilization?

A Granulocyte-colony stimulating factor (G-CSF) ✓
B Erythropoietin (EPO)
C Thrombopoietin (TPO)
D Interleukin-3 (IL-3)

Explanation

G-CSF is a key cytokine involved in the mobilization of hematopoietic stem cells from the bone marrow into the peripheral blood, making it a crucial component of stem cell transplantation protocols.

Source

New England Journal of Medicine
Hematology Hematology: Hematopoiesis Hematology: Hematopoiesis Easy MEDICAL Confidence: high