Which of the following molecules plays a crucial role in the homing of hematopoietic stem cells to the bone marrow niche?

A E-selectin

B P-selectin

C VCAM-1 ✓

D PSGL-1

Explanation

VCAM-1 (Vascular Cell Adhesion Molecule-1) plays a crucial role in the homing of hematopoietic stem cells to the bone marrow niche by facilitating their adhesion to the endothelial cells.

Source

Blood journal

Hematology Hematology: Hematopoiesis Hematology: Hematopoiesis Hard MEDICAL Confidence: medium

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Which of the following molecules plays a crucial role in the homing of hematopoietic stem cells to the bone marrow niche?

Explanation

Source

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