What is the term for the cooperative binding of oxygen to the four subunits of the hemoglobin molecule, resulting in a sigmoidal oxygen-hemoglobin dissociation curve?

A Allosteric effect
B Cooperative binding ✓
C Hemoglobin polymerization
D Oxygen-hemoglobin affinity

Explanation

The cooperative binding of oxygen to the four subunits of the hemoglobin molecule results in a sigmoidal oxygen-hemoglobin dissociation curve, which allows for more efficient oxygen transport.

Source

Guyton and Hall Textbook of Medical Physiology
Hematology Hematology: Hemoglobin and Oxygen Transport Hematology: Hemoglobin and Oxygen Transport Medium MEDICAL Confidence: high