Which of the following enzymes is responsible for converting hemoglobin to biliverdin during the process of heme catabolism?

A Heme oxygenase ✓
B Biliverdin reductase
C Uroporphyrinogen decarboxylase
D Ferrochelatase

Explanation

Heme oxygenase is the enzyme responsible for converting heme to biliverdin, which is then further broken down into bilirubin. This process is essential for recycling iron from senescent red blood cells.

Source

Robbins and Cotran Pathologic Basis of Disease
Hematology Hematology: Hemoglobin and Oxygen Transport Hematology: Hemoglobin and Oxygen Transport Hard MEDICAL Confidence: high