What is the significance of the differences in the globin chain composition between adult hemoglobin and fetal hemoglobin?

A Increased oxygen affinity in adult hemoglobin
B Decreased oxygen affinity in fetal hemoglobin
C Facilitated transfer of oxygen from mother to fetus ✓
D Enhanced carbon dioxide transport in adult hemoglobin

Explanation

The differences in globin chain composition between adult hemoglobin (HbA) and fetal hemoglobin (HbF) allow for the facilitated transfer of oxygen from the mother's bloodstream to the fetus, ensuring adequate oxygen supply to the developing fetus.

Source

Guyton and Hall Textbook of Medical Physiology
Hematology Hematology: Hemoglobin and Oxygen Transport Hematology: Hemoglobin and Oxygen Transport Medium MEDICAL Confidence: high