What is the role of the enzyme Lysosomal acid lipase in the human body, and its deficiency associated with?

A Breaking down triglycerides and cholesterol esters, and its deficiency associated with Wolman disease ✓
B Synthesizing triglycerides and cholesterol esters, and its deficiency associated with Gaucher's disease
C Regulating blood sugar levels, and its deficiency associated with Diabetes mellitus
D Maintaining bone health, and its deficiency associated with Osteoporosis

Explanation

Lysosomal acid lipase is an enzyme responsible for breaking down triglycerides and cholesterol esters in the lysosomes. Its deficiency is associated with Wolman disease, a rare genetic disorder characterized by the accumulation of lipids in various organs.

Source

National Center for Biotechnology Information
Enzymes in Disease Biochemistry Lysosomal storage diseases Hard MEDICAL Confidence: high