Which enzyme's abnormal activity is implicated in the development of Parkinson's disease?

A Monoamine oxidase B ✓
B Catechol-O-methyltransferase
C Dopamine beta-hydroxylase
D Phenylalanine hydroxylase

Explanation

Monoamine oxidase B (MAO-B) is an enzyme involved in the breakdown of dopamine in the brain. Abnormal activity of MAO-B has been implicated in the development of Parkinson's disease, as it can lead to the degradation of dopamine and contribute to the progression of the disease.

Source

National Institute of Neurological Disorders and Stroke
Enzymes in Disease Neurology Neurodegenerative diseases Medium MEDICAL Confidence: high